Investigation of Hepatitis B, Hepatitis C, and Human Immunodeficiency Virus Seroprevalence in Pregnant Patients Admitted to a Secondary Level Hospital
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Original Article
VOLUME: 5 ISSUE: 3
P: 320 - 324
September 2023

Investigation of Hepatitis B, Hepatitis C, and Human Immunodeficiency Virus Seroprevalence in Pregnant Patients Admitted to a Secondary Level Hospital

Arch Basic Clin Res 2023;5(3):320-324
1. Department of Infectious Diseases and Clinical Microbiology, Harran University, Faculty of Medicine, Şanlıurfa, Türkiye
2. Department of Infectious Diseases and Clinical Microbiology, Cizre Dr. Selahattin Cizrelioğlu State Hospital, Şırnak, Türkiye
3. Department of Obstetrics and Gynecology, Private Mardin Park Hospital, Mardin, Türkiye
No information available.
No information available
Accepted Date: 22.05.2023
Online Date: 22.05.2023
Publish Date: 22.05.2023
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Abstract

Objective

In this study, it was aimed to analyze viral hepatitis and human immunodeficiency virus serology of pregnant patients admitted to Cizre State Hospital.

Methods

Patients admitted to Cizre State Hospital Obstetrics and Gynecology Polyclinic between January 2017 and May 2022 due to pregnancy were included in the study. Hepatitis B surface antigen, hepatitis B surface antibody, hepatitis C virus antibody, human immunodeficiency virus antibody, and anti-HBc IgG values of the pregnant women studied by enzyme-linked immunosorbent assay method were examined.

Results

In the study, 24.22% of pregnant women were examined in terms of viral hepatitis and human immunodeficiency virus disease. The mean age of 4548 pregnant women included in the study was 29 ± 6.07 years. Serologically, hepatitis B surface antigen (93.99%) was the most requested test. Hepatitis B surface antigen positivity was detected in 45 pregnant women (1.05%), and 25 of them (55.55%) did not apply to the Infectious Diseases and Clinical Microbiology outpatient clinic for further examination and treatment. Eighty percent of patients with hepatitis B surface antigen positivity were hepatitis B e antigen-negative chronic hepatitis B virus infection. Hepatitis B surface antibody positivity was 35.68%. Hepatitis B surface antibody positivity was present in 33.79% of pregnant women who were born before 1998, when the routine hepatitis B vaccination program began, and in 47.78% of pregnant women born after 1998. As high as 0.41% of pregnant women were hepatitis C virus antibody positive. All of the 21 pregnant women whose first human immunodeficiency virus antibody tests were positive (0.64%) had negative control human immunodeficiency virus antibody results.

Conclusion

In this study, the low rate (24.22%) of pregnant women were examined in terms of viral hepatitis and HIV disease indicating that more importance should be given to viral hepatitis screening. Hepatitis B surface antigen positivity was detected in 1.05% of pregnant women. It was a positive data that the anti-HBs test was found to be positive at a higher rate (47.78%) in pregnant women born after the routine hepatitis B vaccination was started in our country.

Cite this article as

Çelik M, Altındağ D, Atalay E, İçer B, Ceylan MR. Investigation of hepatitis B, hepatitis C, and human immunodeficiency virus seroprevalence in pregnant patients admitted to a secondary level hospital. Arch Basic Clin Res., 2023;5(3):320-324.

Keywords:
Hepatitis B, pregnancy, HBsAg, anti-HCV, anti-HBs, viral hepatitis