Archives of Basic and Clinical Research
Original Article

Investigation of Hepatitis B, Hepatitis C, and Human Immunodeficiency Virus Seroprevalence in Pregnant Patients Admitted to a Secondary Level Hospital

1.

Department of Infectious Diseases and Clinical Microbiology, Harran University, Faculty of Medicine, Şanlıurfa, Türkiye

2.

Department of Infectious Diseases and Clinical Microbiology, Cizre Dr. Selahattin Cizrelioğlu State Hospital, Şırnak, Türkiye

3.

Department of Obstetrics and Gynecology, Private Mardin Park Hospital, Mardin, Türkiye

Arch Basic Clin Res 2023; 5: 320-324
DOI: 10.5152/ABCR.2023.22051
Read: 356 Downloads: 305 Published: 22 May 2023

Objective: In this study, it was aimed to analyze viral hepatitis and human immunodeficiency virus serology of pregnant patients admitted to Cizre State Hospital.

Methods: Patients admitted to Cizre State Hospital Obstetrics and Gynecology Polyclinic between January 2017 and May 2022 due to pregnancy were included in the study. Hepatitis B surface antigen, hepatitis B surface antibody, hepatitis C virus antibody, human immunodeficiency virus antibody, and anti-HBc IgG values of the pregnant women studied by enzyme-linked immunosorbent assay method were examined.

Results: In the study, 24.22% of pregnant women were examined in terms of viral hepatitis and human immunodeficiency virus disease. The mean age of 4548 pregnant women included in the study was 29 ± 6.07 years. Serologically, hepatitis B surface antigen (93.99%) was the most requested test. Hepatitis B surface antigen positivity was detected in 45 pregnant women (1.05%), and 25 of them (55.55%) did not apply to the Infectious Diseases and Clinical Microbiology outpatient clinic for further examination and treatment. Eighty percent of patients with hepatitis B surface antigen positivity were hepatitis B e antigen-negative chronic hepatitis B virus infection. Hepatitis B surface antibody positivity was 35.68%. Hepatitis B surface antibody positivity was present in 33.79% of pregnant women who were born before 1998, when the routine hepatitis B vaccination program began, and in 47.78% of pregnant women born after 1998. As high as 0.41% of pregnant women were hepatitis C virus antibody positive. All of the 21 pregnant women whose first human immunodeficiency virus antibody tests were positive (0.64%) had negative control human immunodeficiency virus antibody results.

Conclusion: In this study, the low rate (24.22%) of pregnant women were examined in terms of viral hepatitis and HIV disease indicating that more importance should be given to viral hepatitis screening. Hepatitis B surface antigen positivity was detected in 1.05% of pregnant women. It was a positive data that the anti-HBs test was found to be positive at a higher rate (47.78%) in pregnant women born after the routine hepatitis B vaccination was started in our country.

Cite this article as: Çelik M, Altındağ D, Atalay E, İçer B, Ceylan MR. Investigation of hepatitis B, hepatitis C, and human immunodeficiency virus seroprevalence in pregnant patients admitted to a secondary level hospital. Arch Basic Clin Res., 2023;5(3):320-324.

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